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For individuals who invested in Nvidia inventory again within the day and held on, the returns have been staggering. It has delivered a 10-year annualised return of 75.3% in sterling phrases.
One FTSE 250 funding belief that has benefited is Baillie Gifford US Development Belief. Between March 2018 and late 2025, its funding in Nvidia went up 3,155%!
Given Baillie Gifford’s observe document of unearthing prime development shares like Nvidia and Tesla, it’s price maintaining a tally of what new shares it has been shopping for. And one new title within the US Development Belief’s portfolio caught my eye.
Let’s take a better take a look at this under-the-radar firm — which just lately went public and is already one of many belief’s bigger holdings — to see what the fuss is about.
The inventory
BillionToOne (NASDAQ:BLLN) is a medical diagnostics firm. Its Quantitative Counting Templates platform is the one patented know-how that may rely DNA molecules with singular precision at a big scale.
Having dug into the agency, I see just a few engaging issues right here. For starters, BillionToOne is working in two high-growth diagnostics markets: non-invasive prenatal and most cancers testing. The agency estimates its complete addressable market at roughly $100bn within the US alone.
It’s encouraging to see the agency profiting from this chance, with Q3 income surging 117% 12 months on 12 months to $83.5m. It delivered 165,000 checks, a rise of 52%.
Administration is guiding for 2026 income of $415m to $430m, which might signify development of 40% to 45%. Most of its income comes from prenatal checks, which display screen for circumstances like cystic fibrosis and sickle cell utilizing solely the mom’s blood, however its most cancers checks are rising very strongly.
One other constructive is that the corporate isn’t burning by means of money. It expects to report constructive full-year working revenue, with sturdy gross margins of about 70%. So this has the potential to be a really high-margin enterprise.
Lastly, the corporate’s market cap at present is simply $3.9bn. At the moment, that’s actually not very huge. The agency may turn into a lot bigger if it seizes the industrial alternative forward.
In any case, Nvidia’s market cap was roughly this measurement again in 2013.
Our long-term purpose is to construct a category-defining generational firm and turn into a member of the S&P 500. BillionToOne
My preliminary takeaway
Stepping again, I see just a few issues right here that point out BillionToOne may turn into a prime development inventory. Not like many early-stage development companies, it’s already guiding for sturdy margins and sustained profitability by means of 2026.
On prime of this, there’s strong institutional investor backing and a large worldwide enlargement alternative. It’s additionally engaged on checks that detect most cancers early, which may turn into probably the most thrilling market of all.
Nevertheless, it’s far too early to name this one a slam-dunk winner, not to mention assign it Nvidia-esque potential. There’s loads of competitors on this house from Guardant Well being and Natera, and I fear a brand new diagnostic breakthrough would possibly threaten the agency’s know-how sooner or later.
In the meantime, the price-to-sales a number of is sort of 10, so there’s loads of development already baked into the present valuation.
For now, I reckon it’s one to keep watch over. BillionToOne will report This autumn earnings in early March.
